Mooreville, sometimes misspelled as Mooresville, is an unincorporated census-designated place located in Lee County, Mississippi.It is part of the Tupelo Micropolitan Statistical Area. Mooreville is approximately 4 miles west of Dorsey and approximately 4 miles east of Tupelo on Mississippi Highway 178 near Interstate 22. It was named for the Moore family, its first settlers.Although an unincorporated community, Mooreville has a post office and a zip code.